A System to Study Aneuploidy In Vivo
نویسندگان
چکیده
منابع مشابه
A System to Study Aneuploidy In Vivo.
Aneuploidy, an imbalanced chromosome number, is associated with both cancer and developmental disorders such as Down syndrome (DS). To determine how aneuploidy affects cellular and organismal physiology, we have developed a system to evaluate aneuploid cell fitness in vivo. By transplanting hematopoietic stem cells (HSCs) into recipient mice after ablation of recipient hematopoiesis by lethal i...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Symposia on Quantitative Biology
سال: 2015
ISSN: 0091-7451,1943-4456
DOI: 10.1101/sqb.2015.80.027193